Indonesian jamu-induced hyperestrogenism with endometrial polyp as a cause of Dysfunctional Uterine Bleeding in Adolescence: A case report

Indonesian traditional medicine or jamu is associated with increased estrogen levels and often consumed for skin beautification reproductive health (1). Endometrial polyps are rare among adolescents (2). We report an unusual case of endometrial in adolescent significant hyperestrogenism. Parental written patient consent was obtained.A 17-year-old girl presented symptomatic anaemia secondary to prolonged heavy bleed. She had been consuming jamu. Clinically, she pale no other physical findings. Transabdominal ultrasonography (TAS) showed thickness (ET) 475mm (Figure 1). While hormonal profiles were normal, her estradiol level 3758 pmol/L. MRI demonstrated ET raising concern hyperplasia malignancy 2). Jamu halted received blood transfusions. Hysteroscopy examination multiple polypoidal structures on the endometrial's right lateral wall. Histopathology revealed benign polyps. discharged well cyclical progestogen. Subsequently, menses regular normal levels.Hyperestrogenism causing thickened lining may be induced by Although rare, polyp should one differential diagnoses presenting bleeding. remains procedure choice rule out relieve symptomsFigure 1. Pelvic ultrasonography, sagittal view showing thickening 4.75cm.Figure 2. Contrast-enhanced CT pelvis, axial at a lower section, obtained. A levels. Hyperestrogenism symptoms Figure 4.75cm. Listia, Tripoli, Faruk Wahyono, Bayu. Traditional (Jamu) modern medical discourse. The International Journal Social Science 2015; 25: 552. Davis VJ, Dizon CD, Minuk CF. Rare cause vaginal bleeding early puberty. J Pediatr Adolesc Gynecol 2005; 18:113